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monalucy
2 Oct 2023

Doctors' Response

What alternatives or suggestions do you have for individuals who are unresponsive to Botox, Dysport, and Xeomin?

For the past seven years, I've been receiving Botox, Dysport, and Xeomin treatments to slim down my lower face by reducing the size of my masseter muscles. Unfortunately, over the past two years, these treatments have become ineffective. It seems I may have developed resistance to Botulinum toxin type A. I'm interested in trying Botulinum toxin type B (Myobloc), but I'm encountering difficulty finding a doctor who offers this less commonly used option.

Replies1
Caner Kacmaz
Dr. Caner Kacmaz
Aesthetic Plastic Surgeon
5 Oct 2023

Botox resistance is very rare. It's estimated that 1 patient out of 10000 develops Botox resistance. The most common reason that Botox does not work is that not enough dose was administered. The same dosage does not work for every patient. Some patients may need additional dosage to reach an effective level of muscle weakness. In some cases, Botox that was used on a patient can be overdiluted or even old. You should always have a follow-up appointment 7 to 10 days after your initial treatment so your doctor can see the results and apply more if needed to correct the problem areas. Good luck.

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